Like other billions of neurons or nerve cells in humans, joi receives signals from the brain and spinal cord, and can affect other neurons by releasing chemicals called neurotransmitters.

However, joi has certain characteristics that makes it unique, for example, it is the one and only neuron that can be regenerated, strengthen and multiplied with different external stimulus (which varies per person and environment)

joi can release Dopamine, a neurotransmitter highly connected to mood and behavior and can also release Serotonin, another chemical that impacts every part of the body, from emotions to motor skills (Serotonin is considered a natural mood stabilizer, helping with sleeping, eating, and digesting)